Table 1.
Genes significantly changed by at least 2-fold difference in pterygium (p < 0.05)
| Up-regulated in pterygium | |||
| Probe ID |
Gene symbol |
Genbank accession | Fold change |
| 209125_at | KRT6A | J00269 | 6.399 |
| 205009_at | TFF1 | NM_003225 | 5.671 |
| 210297_s_at | MSMB | U22178 | 4.175 |
| 211719_x_at | FN1 | BC005858 | 4.112 |
| 212464_s_at | FN1 | X02761 | 3.939 |
| 216442_x_at | FN1 | AK026737 | 3.827 |
| 207811_at | KRT12 | NM_000223 | 3.781 |
| 210495_x_at | FN1 | AF130095 | 3.738 |
| 207430_s_at | MSMB | NM_002443 | 3.732 |
| 202310_s_at | COL1A1 | K01228 | 3.635 |
| 216379_x_at | AK000168 | 3.475 | |
| 209771_x_at | CD24 | AA761181 | 3.42 |
| 218990_s_at | SPRR3 | NM_005416 | 3.401 |
| 201884_at | CEACAM5 | NM_004363 | 3.287 |
| 214385_s_at | MUC5B | AI521646 | 3.244 |
| 202404_s_at | COL1A2 | NM_000089 | 3.149 |
| 205064_at | SPRR1B | NM_003125 | 3.053 |
| 204777_s_at | MAL | NM_002371 | 3.043 |
| 211161_s_at | AF130082 | 2.937 | |
| 219087_at | ASPN | NM_017680 | 2.903 |
| 214303_x_at | MUC5AC | AW192795 | 2.897 |
| 209047_at | AQP1 | AL518391 | 2.773 |
| 213796_at | SPRR1A | AI923984 | 2.772 |
| 205694_at | TYRP1 | NM_000550 | 2.736 |
| 214580_x_at | KRT6A | AL569511 | 2.645 |
| 217272_s_at | SERPINB13 | AJ001698 | 2.545 |
| 218963_s_at | KRT23 | NM_015515 | 2.506 |
| 218353_at | RGS5 | NM_025226 | 2.476 |
| 205547_s_at | TAGLN | NM_003186 | 2.467 |
| 217388_s_at | KYNU | D55639 | 2.441 |
| 201438_at | COL6A3 | NM_004369 | 2.423 |
| 203477_at | COL15A1 | NM_001855 | 2.374 |
| 203980_at | FABP4 | NM_001442 | 2.364 |
| 202311_s_at | COL1A1 | AI743621 | 2.334 |
| 215076_s_at | COL3A1 | AU144167 | 2.331 |
| 213975_s_at | LYZ | AV711904 | 2.322 |
| 209071_s_at | RGS5 | AF159570 | 2.275 |
| 210809_s_at | POSTN | D13665 | 2.261 |
| 202878_s_at | C1QR1 | NM_012072 | 2.242 |
| 217528_at | CLCA2 | BF003134 | 2.226 |
| 204682_at | LTBP2 | NM_000428 | 2.21 |
| 212190_at | SERPINE2 | AL541302 | 2.201 |
| 219410_at | FLJ10134 | NM_018004 | 2.171 |
| 209848_s_at | SILV | U01874 | 2.15 |
| 204351_at | S100P | NM_005980 | 2.114 |
| 204971_at | CSTA | NM_005213 | 2.092 |
| 206427_s_at | MLANA | U06654 | 2.088 |
| 202917_s_at | S100A8 | NM_002964 | 2.084 |
| 203382_s_at | APOE | NM_000041 | 2.081 |
| 211980_at | COL4A1 | AI922605 | 2.077 |
| 200665_s_at | SPARC | NM_003118 | 2.071 |
| 201667_at | GJA1 | NM_000165 | 2.06 |
| 218723_s_at | RGC32 | NM_014059 | 2.056 |
| 203691_at | PI3 | NM_002638 | 2.05 |
| 206276_at | LY6D | NM_003695 | 2.04 |
| 219412_at | RAB38 | NM_022337 | 2.04 |
| 208982_at | PECAM1 | AW574504 | 2.029 |
| 203504_s_at | ABCA1 | NM_005502 | 2.026 |
| 201852_x_at | COL3A1 | AI813758 | 2.01 |
| 203570_at | LOXL1 | NM_005576 | 2.01 |
| Down-regulated in pterygium | |||
| Probe ID | Gene | Genbank accession | Fold change |
| 217232_x_at | HBB | AF059180 | 0.5 |
| 208078_s_at | TCF8 | NM_030751 | 0.499 |
| 201842_s_at | EFEMP1 | AI826799 | 0.496 |
| 201008_s_at | TXNIP | AA812232 | 0.495 |
| 215176_x_at | AW404894 | 0.494 | |
| 206391_at | RARRES1 | NM_002888 | 0.494 |
| 212225_at | SUI1 | AL516854 | 0.492 |
| 201505_at | LAMB1 | NM_002291 | 0.488 |
| 205979_at | SCGB2A1 | NM_002407 | 0.487 |
| 209278_s_at | TFPI2 | L27624 | 0.482 |
| 211003_x_at | TGM2 | BC003551 | 0.479 |
| 211573_x_at | TGM2 | M98478 | 0.479 |
| 202431_s_at | MYC | NM_002467 | 0.475 |
| 213831_at | HLA-DQA1 | X00452 | 0.47 |
| 210095_s_at | IGFBP3 | M31159 | 0.465 |
| 206392_s_at | RARRES1 | NM_002888 | 0.46 |
| 211651_s_at | LAMB1 | M20206 | 0.455 |
| 201843_s_at | EFEMP1 | NM_004105 | 0.443 |
| 202081_at | IER2 | NM_004907 | 0.439 |
| 202340_x_at | NR4A1 | NM_002135 | 0.435 |
| 200664_s_at | DNAJB1 | BG537255 | 0.435 |
| 209116_x_at | HBB | M25079 | 0.431 |
| 215723_s_at | PLD1 | AJ276230 | 0.43 |
| 205910_s_at | CEL | NM_001807 | 0.417 |
| 219759_at | LRAP | NM_022350 | 0.416 |
| 204286_s_at | PMAIP1 | NM_021127 | 0.406 |
| 206424_at | CYP26A1 | NM_000783 | 0.403 |
| 206393_at | TNNI2 | NM_003282 | 0.396 |
| 201466_s_at | JUN | NM_002228 | 0.388 |
| 201464_x_at | JUN | BG491844 | 0.368 |
| 212143_s_at | IGFBP3 | BF340228 | 0.359 |
| 201473_at | JUNB | NM_002229 | 0.356 |
| 217022_s_at | MGC27165 | S55735 | 0.355 |
| 201236_s_at | BTG2 | NM_006763 | 0.342 |
| 204285_s_at | PMAIP1 | AI857639 | 0.301 |
| 201041_s_at | DUSP1 | NM_004417 | 0.296 |
| 201044_x_at | DUSP1 | AA530892 | 0.265 |
| 204622_x_at | NR4A2 | NM_006186 | 0.22 |
| 201694_s_at | EGR1 | NM_001964 | 0.215 |
| 204621_s_at | NR4A2 | AI935096 | 0.192 |
| 213674_x_at | IGHM | AI858004 | 0.188 |
| 216248_s_at | NR4A2 | S77154 | 0.17 |
| 202768_at | FOSB | NM_006732 | 0.167 |
| 202672_s_at | ATF3 | NM_001674 | 0.159 |
| 209189_at | FOS | BC004490 | 0.072 |