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. 2009 Mar 13;10:106. doi: 10.1186/1471-2164-10-106

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Copyright © 2009 Fu et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Joint effects of MCB and genotyping errors on association studies under multiplicative disease model. A) illustrates the overall call-rate for the loci with different values of α in the joint models of MCB and genotyping errors (MAF = 0.25, c = 0.8, conf = 0.0, 0.25, 0.5, 0.75 and 1.0). B) illustrates the genotyping error rate with different values of α in the corresponding joint models. C) illustrates the power based on allelic χ²test with different values of α. D) illustrates the power based on genotypic χ²test with different values of α. The figures correspond to Scenario I, Scenario II, Scenario III and Scenario IV from the left to right.