Skip to main content
. 2009 Mar 13;10:106. doi: 10.1186/1471-2164-10-106

Table 2.

The power under different modes of inheritance relationship in the significant of 0.05.

Disease Models Penetrances (hAA, hAa, haa) Scenarios Power in Allelic χ 2test Power in Genotypic χ 2test

Null MCB UBM Null MCB UBM
I 0.805 0.790 0.800 0.806 0.800 0.800
Dominant (0.0148, 0.0148, 0.01) II & III 0.805 0.799 0.770 0.806 0.762 0.769
IV 0.805 0.730 0.762 0.806 0.756 0.759

I 0.619 0.472 0.611 0.801 0.710 0.794
Recessive (0.0201, 0.01, 0.01) II & III 0.619 0.691 0.586 0.801 0.798 0.769
IV 0.619 0.599 0.569 0.801 0.796 0.751

I 0.495 0.536 0.490 0.796 0.792 0.791
Overdominant (0.01, 0.0148, 0.01) II & III 0.495 0.447 0.461 0.796 0.736 0.758
IV 0.495 0.406 0.453 0.796 0.757 0.748

I 0.869 0.831 0.864 0.800 0.770 0.793
Additive (0.0178, 0.0139, 0.01) II & III 0.869 0.880 0.840 0.800 0.776 0.763
IV 0.869 0.816 0.831 0.800 0.756 0.752

I 0.875 0.831 0.870 0.800 0.763 0.793
Multiplicative (0.01847, 0.01359, 0.01) II & III 0.875 0.889 0.847 0.800 0.782 0.763
IV 0.875 0.826 0.838 0.800 0.759 0.752

MAF is 0.25 and the sample size in case and control is 500 respectively. Null, the power in absence of missing; MCB, the power affected by missing call bias; UBM, the power when missing equivalently but unbiasedly across different genotypes.