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. Author manuscript; available in PMC: 2009 Apr 20.
Published in final edited form as: J Thromb Haemost. 2007 Oct 8;5(12):2494–2502. doi: 10.1111/j.1538-7836.2007.02785.x

Fig. 6. Asp135 in the GPIX TM domain is important to complex assembly and expression.

Fig. 6

(A) Surface expression levels of GPIbα (gray) and GPIX (white), as well as (B) overall expression of GPIbα and GPIX, in Asp135 mutant cells were measured as described earlier. The relative intensity marked under each band is the average of 3 independent experiments. (C) GPIb formation in Asp135 mutant cells. Cell lysates were resolved in non-reducing SDS gels and immunoblotted with WM23. The blot shown represents 3 independent experiments.