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. Author manuscript; available in PMC: 2009 Apr 20.
Published in final edited form as: J Thromb Haemost. 2007 Oct 8;5(12):2494–2502. doi: 10.1111/j.1538-7836.2007.02785.x

Fig. 7. Probing the interaction between Asp135 of GPIX and Gln129 of GPIbβ.

Fig. 7

(A) The TM sequences (underlined) of GPIbβ and GPIX. Residues Gln129 of GPIbβ and Asp135 of GPIX are boxed. (B,C) Effects of mutating Gln129 and Asp135 to certain polar residues on surface expression levels of GPIbα (gray bar) and GPIX (white bar), GPIb formation as well as overall expression of the complex. The data shown were either the average or a representative of 3–4 independent experiments.