Figure 1. Electrophoretic Mobility Shift Assay (EMSA) of STAT-3 DNA Binding Activity following Sham Operation (SO), Single Puncture CLP (CLP) and Double Puncture CLP (2CLP).
Top: Autoradiogram of representative EMSA detailing STAT-3 DNA binding activity following SO, CLP or 2CLP. Subscript indicates time (hrs) following intervention. CC - cold competition, SS - supershift. Bottom: quantification of densitometrically-determined relative STAT-3 DNA Binding Activity of STAT-3 following SO, CLP or 2CLP. Each data point represents mean ± SD of values from 3 different animals. Time following intervention on x-axis. * - value significantly different from To. ^ - value significantly different from value for SO at same time point. # - value for 2CLP significantly different from value for CLP at same time point.