Table 1.
Time spent struggling or swimming in the forced swim test of in the forced swim test of male (left) and female (right) mice administered oil vehicle (veh), testosterone (T), dihydrotestosterone (DHT), 3α-androstanediol (3α-diol), or estradiol (E2). Data are expressed as means in seconds ± s.e.m.
| Measure | Condition | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Male | Female | |||||||||
| veh | T | DHT | 3α-diol | E2 | veh | T | DHT | 3α-diol | E2 | |
| n | 6 | 5 | 4 | 5 | 6 | 4 | 4 | 4 | 4 | 4 |
| Time spent struggling | 36.5 ± 17.8 | 57.0 ± 24.1 | 107.8 ± 5.9 | 83.4 ± 19.5 | 114.5 ± 6.4 | 14.3 ±5.3 | 101.5 ± 3.6 | 107.8 ± 10.8 | 104.0 ± 5.7 | 31.5 ± 8.6* |
| Time spent swimming | 43.0 ± 8.2 | 54.4 ± 13.8 | 35.8 ± 9.5 | 48.4 ± 11.2 | 29.2 ± 3.2 | 103.5 ± 5.5* | 44.5 ± 9.4 | 35.5 ± 9.9 | 35.5 ± 4.8 | 114.3 ± 5.1* |
*
indicates a significant interaction between main effects.