Table 2.
Anthropometric and dual x-ray absorptiometry–derived body composition characteristics and phenotypes for women and men with RA versus matched non-RA controls*
| Women |
Men |
|||||
|---|---|---|---|---|---|---|
| RA (n = 117) |
Non-RA (n = 117) |
P | RA (n = 72) |
Non-RA (n = 72) |
P | |
| Weight, kg | 74.4 ± 16.0 | 70.1 ± 13.9 | 0.031 | 88.2 ± 17.0 | 87.7 ± 13.7 | 0.837 |
| Body mass index, kg/m2 | 28.3 ± 5.6 | 26.2 ± 4.8 | 0.002 | 28.7 ± 5.0 | 28.1 ± 4.2 | 0.416 |
| Underweight, no. (%)† | 1 (0.9) | 1 (0.9) | 1.000 | 0 (0) | 0 (0) | 1.000 |
| Normal weight, no. (%)‡ | 36 (30.8) | 58 (49.6) | 0.002 | 16 (22.2) | 20 (27.8) | 0.441 |
| Overweight, no. (%)§ | 42 (35.9) | 29 (24.8) | 0.065 | 30 (41.7) | 31 (43.1) | 0.866 |
| Obese, no. (%)¶ | 38 (32.5) | 29 (24.8) | 0.193 | 26 (36.1) | 21 (29.2) | 0.374 |
| Total fat mass, kg | 31.5 ± 10.7 | 28.0 ± 10.3 | 0.012 | 27.3 ± 10.3 | 25.9 ± 9.9 | 0.414 |
| Fat mass index, kg/m2 | 12.0 ± 4.0 | 10.4 ± 3.7 | 0.002 | 8.9 ± 3.3 | 8.3 ± 3.2 | 0.280 |
| Truncal fat mass, kg | 16.0 ± 14.1 | 14.1 ± 5.9 | 0.015 | 16.5 ± 6.4 | 15.4 ± 6.2 | 0.312 |
| Body fat percentage | 42.1 ± 7.2 | 38.7 ± 7.6 | < 0.001 | 30.4 ± 7.5 | 28.9 ± 8.0 | 0.294 |
| Total lean mass, kg | 39.3 ± 6.9 | 40.0 ± 4.9 | 0.419 | 56.9 ± 8.4 | 58.8 ± 8.3 | 0.196 |
| Appendicular lean mass, kg | 16.1 ± 3.3 | 16.4 ± 2.4 | 0.531 | 24.7 ± 3.9 | 26.1 ± 3.9 | 0.039 |
| Relative skeletal muscle index, kg/m2 | 6.8 ± 1.2 | 6.8 ± 0.9 | 0.811 | 9.2 ± 1.2 | 9.5 ± 1.4 | 0.130 |
| Skeletal muscle mass to fat mass ratio | 0.63 ± 0.23 | 0.72 ± 0.26 | 0.006 | 1.24 ± 0.74 | 1.26 ± 0.50 | 0.850 |
| Sarcopenia, no. (%) | 25 (21.4) | 9 (7.7) | 0.004 | 24 (33.3) | 16 (22.2) | 0.157 |
| Overfat, no. (%) | 67 (57.3) | 41 (35.0) | 0.001 | 41 (56.9) | 36 (50.0) | 0.423 |
| Sarcopenic obesity, no. (%) | 13 (11.1) | 3 (2.6) | 0.008 | 11 (15.3) | 8 (11.1) | 0.467 |
*
Values are the mean ± SD unless otherwise indicated. RA = rheumatoid arthritis.
†
BMI 18.50 kg/m2.
‡
BMI 18.50–24.99 kg/m2.
§
BMI 25.00–29.99 kg/m2.
¶
BMI ≥30 kg/m2.