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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Clin Cancer Res. 2008 Dec 1;14(23):7711–7716. doi: 10.1158/1078-0432.CCR-08-1364

Fig. 4.

Fig. 4

Splenocytes from combination-treated mice are active in vitro. A, ELISPOT analysis for IFN-γ. Splenocytes harvested from mice treated with both G47Δ and iDCs were more likely to produce IFN-γ on stimulation with irradiated N18 cells. Average of three mice from each treatment group. SFC, spot-forming cells. * P < 0.05. B, cleaved caspase-3 CTL assay. A significantly higher percentage of DDAO-labeled N18 target cells expressed cleaved caspase-3 after coincubation with splenocyte effectors harvested from mice whose tumors had been treated with G47Δ and iDCs than when coincubated with cells from animals in other treatment groups. Average of four mice from each treatment group. E, effector cells; T, target cells. Bars, SD.