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Effects of loading frequency on solute desorption (hydrodynamic radius: 3 nm) in the samples with tension-compression nonlinearity (H+A / H−A =16). In the simulations, the cartilage samples were subjected to dynamic compressive loading with a frequency of either 0.1 Hz, 0.01 Hz, or 0.001 Hz and strain amplitude of 5% for 5000 sec.
