. Author manuscript; available in PMC: 2009 Apr 21.

Published in final edited form as: Cell Metab. 2006 Jul;4(1):75–87. doi: 10.1016/j.cmet.2006.05.002

Table 1.

Expression of genes involved in mitochondrial biogenesis, fiber type determination, and fat oxidation in 12-week-old wt and adiponectin-deficient mice

		Wild-Type	Adiponectin KO

Gene	Muscle	mRNA/ RPLPO	mRNA (Arbitrary Units)
PGC1α	Soleus	348 ± 13	201 ± 32^a
	Gastrocnemius	224 ± 20^b	158 ± 11^a,^b
PGC1β	Soleus	4.3 ± 0.4	3.4 ± 0.9
	Gastrocnemius	2.9 ± 0.7^b	3.6 ± 0.5
NRF-1	Soleus	18 ± 1	18 ± 2
	Gastrocnemius	23 ± 2	16 ± 0.6
PPARδ	Soleus	113 ± 4	85 ± 7^a
	Gastrocnemius	124 ± 11	98 ± 6^a
PPARα	Soleus	94 ± 10	79 ± 12
	Gastrocnemius	32 ± 12^b	27 ± 6^b
UCP3	Soleus	65 ± 21	69 ± 19
	Gastrocnemius	85 ± 18	129 ± 48

PGC1α, peroxisome proliferative activated receptor gamma coactivator-1 alpha; PGC1β, peroxisome proliferative activated receptor gamma coactivator-1 beta; NRF1, nuclear respiratory factor 1; PPARδ, peroxisome proliferative activated receptor-delta; PPARα, peroxisome proliferative activated receptor-alpha; and UCP3, uncoupling protein 3. Data represented mean ± SEM, n = 5 each group.

p < 0.05 compared to wt mice.

p < 0.05 compared to soleus.