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. 2009 Feb 10;58(5):1192–1200. doi: 10.2337/db08-1266

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© 2009 by the American Diabetes Association.

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FIG. 3. — A: Gonadal fat expression of genes related to mitochondrial biogenesis and thermogenesis by RT-PCR. *P < 0.05 vs. CC. mRNA abundance is normalized to expression of the housekeeping gene cyclophilin. Gene expression in the C-C group is set as 1. B: Abundance of the mitochondrial-encoded gene Cox-2 relative to the nuclear-encoded gene β-globin in gonadal fat pads. The relative proportion of Cox-2 to β-globin is proportional to the amount of mitochondrial DNA per cell. *P < 0.05. C: Abundance of the mitochondrial-encoded gene ND-1 relative to the nuclear-encoded gene β-globin in gonadal fat pads. The relative proportion of ND-1 to β-globin is proportional to the amount of mitochondrial DNA per cell. , C-U; ■, U-C; ▨, U-U.

Inline graphic — A: Gonadal fat expression of genes related to mitochondrial biogenesis and thermogenesis by RT-PCR. *P < 0.05 vs. CC. mRNA abundance is normalized to expression of the housekeeping gene cyclophilin. Gene expression in the C-C group is set as 1. B: Abundance of the mitochondrial-encoded gene Cox-2 relative to the nuclear-encoded gene β-globin in gonadal fat pads. The relative proportion of Cox-2 to β-globin is proportional to the amount of mitochondrial DNA per cell. *P < 0.05. C: Abundance of the mitochondrial-encoded gene ND-1 relative to the nuclear-encoded gene β-globin in gonadal fat pads. The relative proportion of ND-1 to β-globin is proportional to the amount of mitochondrial DNA per cell. , C-U; ■, U-C; ▨, U-U.