TABLE 1.
Cognitive test scores during euglycemia and hypoglycemia with medium-chain triglycerides or placebo ingestion
Cognitive test | Medium-chain triglycerides euglycemia (∼5.5 mmol · l−1 · l−1) | Medium-chain triglycerides hypoglycemia (∼2.8 mmol · l−1 · l−1) | Placebo euglycemia (∼5.5 mmol · l−1 · l−1) | Placebo hypoglycemia (∼2.8 mmol · l−1 · l−1) |
---|---|---|---|---|
Immediate verbal memory | 15.85 ± 0.66 | 14.97 ± 1.13* | 17.36 ± 1.03 | 13.28 ± 1.04† |
Delayed verbal memory | 14.82 ± 1.25 | 14.80 ± 1.31* | 15.33 ± 1.40 | 11.58 ± 0.71† |
Verbal memory recognition | 13.19 ± 0.53 | 13.29 ± 0.50* | 14.27 ± 0.23 | 12.14 ± 0.19† |
Digit span backwards | 0.60 ± 0.05 | 0.58 ± 0.05 | 0.64 ± 0.05 | 0.54 ± 0.05† |
Letter/number sequencing | 12.04 ± 0.81 | 10.97 ± 0.76 | 11.07 ± 0.85 | 9.92 ± 0.71 |
Digit symbol coding | 72.50 ± 5.27 | 74.99 ± 4.56* | 74.04 ± 4.59 | 68.56 ± 3.54† |
Map search (1 min) | 53.11 ± 4.16 | 48.42 ± 3.19 | 50.35 ± 3.27 | 42.94 ± 2.31† |
Map search (2 min) | 73.30 ± 1.70 | 75.11 ± 1.51* | 75.04 ± 1.92 | 74.67 ± 1.51 |
Telephone search | 2.86 ± 0.17 | 3.06 ± 0.20 | 3.14 ± 0.26 | 3.46 ± 0.34 |
Data are least square means ± SE.
*P < 0.05 change from euglycemia to hypoglycemia after medium-chain triglycerides vs. placebo;
†P < 0.05 between euglycemia and hypoglycemia.