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. 2009 Feb 10;58(5):1156–1164. doi: 10.2337/db08-0800

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© 2009 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 6. — Adoptive transfer of purified activated G9Cα^−/−.NOD CD8 T-cells into NOD.scid mice. G9Cα^−/−.NOD CD8 T-cells were purified and cultured with matured bone marrow–derived dendritic cells together with 0.5 μg/ml insulin B15-23 peptide for 3 days. After washing, the cells were intravenously injected into 6-week-old NOD.scid mice (n = 8). Mice were tested daily for glycosuria and diabetes confirmed by blood glucose >13.9mmol/l.