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. Author manuscript; available in PMC: 2009 Apr 21.
Published in final edited form as: Arthritis Rheum. 2008 Sep;58(9):2632–2641. doi: 10.1002/art.23766

Table 2.

Univariate regression coefficients for associations of the log CRP with clinical and demographic characteristics among male and female subjects*

Male
 Female
Characteristic β P R2 β P R2
Demographic
 Age 0.037 0.017 0.073 −0.002 NS <0.001
 Caucasian −0.547 NS 0.018 −0.722 0.043 0.035
 Current smoker 0.218 NS 0.004 −0.299 NS 0.004
 Diabetes 0.175 NS 0.001 −0.529 NS 0.007
 Dyslipidemia 0.549 NS 0.024 0.362 NS 0.150
RA
 Duration of RA, years 0.049 <0.001 0.142 0.017 NS 0.008
 Swollen joint count 0.078 0.014 0.076 0.020 NS 0.005
 Tender joint count 0.010 NS 0.004 −0.015 NS 0.012
 HAQ score 0.363 NS 0.029 0.224 NS 0.015
 Joint deformity 0.049 0.043 0.053 0.024 NS 0.019
 Glucocorticoid use 0.101 NS 0.012 0.015 NS 0.009
 Nonbiologic DMARD use 0.169 NS 0.002 0.031 NS <0.001
 Biologic DMARD use −0.696 0.032 0.059 −0.322 NS 0.014
Body composition
 Weight −0.002 NS 0.004 0.013 <0.001 0.104
 Body mass index† −0.033 NS 0.014 0.096 <0.001 0.152
 Body fat percentage −0.006 NS 0.001 0.084 <0.001 0.192
 Total fat mass† −0.006 NS 0.002 0.052 <0.001 0.164
 Truncal fat mass† −0.023 NS 0.024 0.106 <0.001 0.226
 Total lean mass† −0.036 NS 0.042 0.041 0.062 0.039
Physical activity
 Daily exercise −0.256 NS 0.009 −0.684 0.006 0.063
 Hours of sedentary activity 0.092 NS 0.012 0.189 0.027 0.041
*

Values for the regression coefficient represent the unit change in the log C-reactive protein (CRP) level (logarithmically transformed to normality using the natural log) per unit change in characteristic (for age, duration of rheumatoid arthritis [RA], swollen joint count, tender joint count, Health Assessment Questionnaire [HAQ] score, joint deformity, all body composition measures, and hours of sedentary activity) or the difference in the mean CRP level for subjects with versus those without the characteristic (for Caucasian, current smoker, diabetes, dyslipidemia, use of glucocorticoids or of either type of disease-modifying antirheumatic drugs [DMARDs], or daily exercise). Sedentary activity is defined as duration of daily television watching. Statistically significant interactions of sex in the body composition–log CRP association were detected in all univariate and multivariate models; thus, all analyses are presented stratified by sex. R2 = coefficient of determination; NS = not statistically significant.

†

Regression coefficient adjusted for height.