Table 2.
Glucose tolerance, insulin sensitivity, and release
| Normal-weight black | Normal-weight white | Obese black | Obese white | |
|---|---|---|---|---|
| n | 13 | 14 | 16 | 14 |
| FSIGT | ||||
| SI (× 10−5 min−1/[pmol/l]) | 4.4 ± 0.8* | 9.4 ± 0.8* | 2.9 ± 0.8§ | 6.0 ± 0.8§ |
| AIRg (pmol/l) | 171.3 ± 42.5** | 58.6 ± 41.0** | 328.0 ± 38.2§ | 78.2 ± 41.0§ |
| Disposition index (× 10−5 min−1) | 3,811 ± 538 | 2,966 ± 518 | 3,646 ± 485 | 2,353 ± 518 |
| Sg (× 10−1 min) | 0.25 ± 0.03 | 0.24 ± 0.02 | 0.28 ± 0.02 | 0.24 ± 0.02 |
| Kg (%/min) | 2.81 ± 0.35 | 2.44 ± 0.34 | 3.46 ± 0.31* | 2.22 ± 0.34* |
| OGTT | ||||
| Fasting glucose (mmol/l) | 4.5 ± 0.1 | 4.4 ± 0.1 | 4.6 ± 0.1 | 4.7 ± 0.1 |
| Fasting insulin (pmol/l) | 59.0 ± 8.0* | 28.5 ± 7.7*§ | 90.6 ± 7.2‡ | 52.5 ± 7.7§‡ |
| Δinsulin(0–30)/Δglucose(0–30) | 437 ± 70* | 184 ± 65* | 507 ± 65† | 248 ± 65† |
| DIo (mmol/l) | 7.7 ± 1.3 | 7.6 ± 1.2 | 5.1 ± 1.2 | 5.0 ± 1.2 |
Values are unadjusted means ± SEM. All P values were adjusted for age.
*,†,‡,§Matching superscript symbols represent groups that are significantly different from each other, P < 0.05;
**P < 0.01.