Table 2.
Incidence of acute pancreatitis associated with type 2 diabetes stratified by age and sex from a retrospective claims database study, 2000–2005
Nondiabetic cohort |
Type 2 diabetic cohort |
IRR: type 2 diabetic cohort vs. nondiabetic cohort (95% CI) | |||||||
---|---|---|---|---|---|---|---|---|---|
n * | Incident cases | Person-years of follow-up | Incidence rate per 100,000 person-years (95% CI) | n | Incident cases | Person-years of follow-up | Incidence rate per 100,000 person-years (95% CI) | ||
Overall age | 336,410 | 827 | 553,959.28 | 149.29 (139.11–159.46) | 334,930 | 2,551 | 604,684.35 | 421.87 (405.50–438.24) | 2.83 (2.61–3.06) |
18–30 years | 13,628 | 9 | 17,029.62 | 52.85 (18.32–87.38) | 13,553 | 81 | 19,780.12 | 409.50 (320.32–498.68) | 7.75 (3.89–15.43) |
31–44 years | 78,518 | 105 | 120,783.10 | 86.93 (70.30–103.56) | 78,051 | 584 | 132,996.11 | 439.11 (403.50–474.72) | 5.05 (4.10–6.22) |
45–54 years | 120,354 | 272 | 200,359.38 | 135.76 (119.62–151.89) | 119,823 | 862 | 217,352.86 | 396.59 (370.11–423.07) | 2.92 (2.55–3.35) |
55–64 years | 91,859 | 273 | 154,084.70 | 177.18 (156.16–198.19) | 91,526 | 723 | 167,069.73 | 432.75 (401.21–464.30) | 2.44 (2.13–2.81) |
≥65 years | 32,051 | 168 | 61,702.48 | 272.27 (231.10–313.45) | 31,977 | 301 | 67,485.52 | 446.02 (395.63–496.41) | 1.64 (1.36–1.98) |
Sex | |||||||||
Female | 148,868 | 370 | 242,728.54 | 152.43 (136.90–167.97) | 148,288 | 1058 | 267,658.93 | 395.28 (371.46–419.10) | 2.59 (2.30–2.92) |
Male | 187,542 | 457 | 311,230.74 | 146.84 (133.37–160.30) | 186,642 | 1493 | 337,025.42 | 442.99 (420.52–465.46) | 3.02 (2.72–3.35) |
*Patients with events of acute pancreatitis (n = 594 from the nondiabetic cohort and n = 1,883 from the type 2 diabetic cohort) or chronic pancreatitis (n = 162 from the nondiabetic cohort and n = 656 from the type 2 diabetic cohort) during the 1-year baseline period were excluded from the numerator and the denominator. In addition, patients with chronic pancreatitis during follow-up were excluded (n = 26 from the nondiabetic cohort and n = 161 from the type 2 diabetic cohort). Note that some patients may have had more than one exclusionary event.