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. Author manuscript; available in PMC: 2010 Jan 5.
Published in final edited form as: Eur J Pharmacol. 2008 Nov 11;602(1):92–100. doi: 10.1016/j.ejphar.2008.11.004

Figure 5.

Figure 5

Dose-ratios for each drug alone and each drug mixture for production of rate suppression and thermal nociception. Abscissa: Identity of drug or drug mixture. Ordinate: Dose ratio determined as ED50 (or Zmix) in assay of schedule-controlled responding ÷ ED50 (or Zmix) in assay of thermal nociception. * Asterisks indicate that drug mixture was significantly more potent in the assay of thermal nociception as determined by non-overlapping confidence limits of ED50 or Zmix values (i.e. Dose Ratio ≥1). † Crosses indicate that drug mixture was significantly less potent in the assay of thermal nociception as determined by non-overlapping confidence limits (i.e. Dose Ratio <1).