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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: J Am Soc Mass Spectrom. 2008 Sep 12;20(1):89–95. doi: 10.1016/j.jasms.2008.09.008

Figure 1.

Figure 1

Traditional method and the modified sandwich method for tissue imaging. Snap frozen tissue is cut in 10-20 μm slices and mounted on a conductive MALDI plate. A. Sinapinic acid (SA) sprayed with a nebulizer or spotted either by hand or with a robot 10. B. In the modified sandwich method a 14 μm slice of frozen tissue is processed as illustrated and described in detail in the text.