Table 2.
Average Percentages of GFP+CD163+ Cells Within CNS Tissues
| Animal | Tissue | EGFP+CD163+ cells versus all EGFP+ cells (%)* | EGFP+CD163+ cells versus all CD163+ cells (%)† | n |
|---|---|---|---|---|
| CJ5B | Choroid plexus | 40 ± 8 | 3 ± 1 | 8 |
| Cerebellum | 37 ± 6 | 15 ± 3 | 5 | |
| Cerebrum (frontal lobe) | 60 ± 10 | 4 ± 1 | 9 | |
| RQ3556 | Choroid plexus | 27 ± 11 | 1 ± 0 | 10 |
| Cerebellum | 44 ± 10 | 4 ± 1 | 8 | |
| Cerebrum | ND | ND | ||
| RQ3570 | Choroid plexus | 72 ± 8 | 3 ± 1 | 6 |
| Cerebellum | 85 ± 7 | 6 ± 1 | 6 | |
| Cerebrum (frontal lobe) | 77 ± 7 | 2 ± 1 | 6 |
n is the number of tissue sections from which EGFP+CD163−, EGFP+CD163+ and EGFP−CD163+ cells were counted. For choroid plexus sections, four arbitrary microscope fields were counted per sections.
*
Mean ± SD of the percentage of EGFP+ cells expressing CD163 calculated as followed: (number of EGFP+CD163+ cells) / (total number of EGFP+ cells) ×100.
†
Mean ± SD of the percentage of CD163+ cells that derive from transplanted EGFP+ hematopoietic stem cells calculated as followed: (number of EGFP+CD163+ cells) / (total number of CD163+ cells) ×100.
ND denotes not done.