Table 3.
Stage | I | II | III | IV |
---|---|---|---|---|
Vascular smooth muscle cells (VSMC) | Intact | Disruption, disorganization and partial loss | Substantial loss | Little/none remaining |
Endothelium | Intact | Swelling and some breaks | Substantial loss | Little/none remaining |
Endovascular trophoblasts (vEVTs) | Absent | Absent | Present in lumen | Present in lumen and relining vessel |
Fibrinoid | Absent | Absent | Detected in vessel wall | Detected in vessel wall |