Table 3.
Relative abundance of rearrangement | 100–10% | 10–1% | <1% |
---|---|---|---|
Detected by both analyses | 29 | 2 | 6 |
BIOMED-2 only | 1 | 0 | 1 |
Repertoire analysis only | 7 | 1 | 23 |
Repertoire analysis was performed using genomic DNA in 15 children and using pre-amplified DNA in 10. The BIOMED-2 analysis was performed in all 25 using genomic DNA. Rearrangements were grouped by their abundance, assessed as the percentage of the total number of rearranged IGH molecules that each rearrangement contributed in a patient.