Table 3.

Number of Rearrangements of High (100–10%), Intermediate (10–1%), or Low (<1%) Abundance Detected by the Repertoire and/or BIOMED-2 Approaches in the First Study

Relative abundance of rearrangement	100–10%	10–1%	<1%
Detected by both analyses	29	2	6
BIOMED-2 only	1	0	1
Repertoire analysis only	7	1	23

Repertoire analysis was performed using genomic DNA in 15 children and using pre-amplified DNA in 10. The BIOMED-2 analysis was performed in all 25 using genomic DNA. Rearrangements were grouped by their abundance, assessed as the percentage of the total number of rearranged IGH molecules that each rearrangement contributed in a patient.