Figure 1.

Human α-synuclein is overexpressed in cultured oligodendrocytes derived from Tg mice. A: Immunofluorescent staining of cultured oligodendrocytes for CNPase (left) and wild-type human α-syn (right) at DIV21. Cultured oligodendrocytes were derived from non-Tg and Tg mice. A Syn204-positive oligodendrocyte overexpressing human wild-type α-syn was observed in the cultured cells from Tg mice. Scale bar = 100 μm. B: Cell density of the oligodendrocytes overexpressing human wild-type α-syn was obtained by counting Syn204-positive cells over five objective fields in each series of cultures. Means data are plotted from three independent series of cultures. Data are presented as means ± SEM.