Tritiated thymidine uptake expressed as specific activity in the right, R, and left, L, liver lobes of normal dogs with and without hepatic resections. Two doses of [CH3-3H] thymidine were used. Five of the normal dogs from group 1 received 1.5 millicuries; the other six were given 4.5 millicuries. The four dogs of group 5 had 30 per cent liver resections; four days later, they received the smaller thymidine dose, Another four dogs, group 6, were sacrificed three days after 60 per cent resection; they received the larger thymidine dose. Note that 30 per cent resection caused only a slight increase in thymidine uptake, whereas the 60 per cent resection produced a sixfold increase in specific activity. N, Number of experiments.