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. 2009 Apr 28;4(4):e5374. doi: 10.1371/journal.pone.0005374

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Guérin et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A to C (toto) and DE (sections) show Ptn expression. AB show clone 161 and B'CDE show clone 163. Note that expression is diffuse at stage 24 (A, D) and condenses at the dorsal midline at stage 26 (B, B') and 27 (E). Arrows in A point to dorsal telencephalic and dorsal diencephalic expression. Arrows in B indicate a thin line of expression in lower lip (ll) and ventral aspect of the branchial arches. In B' and D, rp indicates the roof plate. Note the difference of expression level at the di-mesencephalic border (arrowhead in B') between the pretectum (pt) and the tectum. In C, the arrows point to the Ptn-expressing tel-diencephalic boundary. E shows an antero-posterior series through the telencephalon and tel-diencephalic boundary, highlighting the relationship of the Ptn pattern and the suspected morphogenetic movements in the vicinity of the pineal gland (p). tdb indicates the telencephalo-diencephalic boundary region. rp, roof plate; dt, dorsal thalamus; p, pineal gland; pt, pretectum.