Table 3.
Characteristics and outcomes of patients with spontaneous bacterial peritonitis due to extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella species (ESBL-EK), according to the effectiveness of the initial therapy
| Characteristics | Initial therapy | P-value | |
|---|---|---|---|
| Effective (n = 8) | Ineffective (n = 18) | ||
| Age (mean in year, SD) | 62.1 ± 9.3 | 58.3 ± 10.4 | 0.363 |
| Male (n, %) | 4 (50%) | 15 (83%) | 0.149 |
| Escherichia coli (n, %) | 5 (63%) | 12 (67%) | 1.000 |
| Child-Pugh score (mean, SD) | 10.4 ± 1.6 | 11.1 ± 1.6 | 0.330 |
| APACHE II score (mean, SD) | 15.6 ± 3.8 | 15.6 ± 3.7 | 0.993 |
| Outcomes | |||
| Initial response† | |||
| Complete response (n, %) | 1 (13%) | 1 (6%) | 0.529 |
| Treatment failure (n, %) | 2 (25%) | 13 (72%) | 0.038 |
| 7-day mortality (n, %) | 1 (13%) | 8 (44%) | 0.190 |
| 30-day mortality (n, %) | 1 (13%) | 11 (61%) | 0.036 |
SD – standard deviation
APACHE II – Acute Physiologic and Chronic Health Evaluation II
† Initial response was assessed 72 hours after the initiation of empirical treatment