Table 2.
Specificity and positive predictive value (PPV) of fever as policy recommendations compared with malaria disease*, stratified by transmission intensity and age categories
Very high transmission districts n/N,% (95% CI) |
Moderate-to-high transmission districts n/N,% (95% CI) |
All districts n/N,% (95% CI) |
|
All age groups | |||
Specificity | 101/403, 25.1 (19.7–30.5) | 208/723, 28.8 (24.7–32.9) | 309/1126, 27.4 (24.2–30.7) |
PPV | 175/477, 36.7 (32.1–41.3) | 184/699, 26.3 (22.4–30.3) | 359/1176, 30.5 (27.4–33.6) |
Patients <5 years | |||
Specificity | 16/102, 15.7 (7.9–23.4) | 40/190, 21.1 (15.8–26.3) | 56/292, 19.2 (14.9–23.5) |
PPV | 104/190, 54.7 (49.1–60.4) | 98/248, 39.5 (31.8–47.3) | 202/438, 46.1 (41.0–51.3) |
Patients ≥5 years | |||
Specificity | 85/301, 28.2 (21.7–34.7) | 168/533, 31.5 (26.4–36.6) | 253/834, 30.3 (26.4–34.3) |
PPV | 71/287, 24.7 (20.0–29.5) | 86/451, 19.1 (15.1–23.0) | 157/738, 21.3 (18.2–24.3) |
* Defined as any malaria parasitaemia on expert slide examination in patient with fever