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Periodontitis as multifactorial disease: development of periodontal disease from bacterial challenge producing plaque to severe disease. Abbreviations: Fcγ: Fcγ-receptors; IL-1: polymorphisms of interleukin-1 clusters; MMP-1: metalloproteinase-1 (collagenase); MPO: myeloperoxidase; NAT2: N-acetyltransferase 2.
