Table 1. Viscosity and aggregation state of surfactants with and without polymers.
| Surfactant | Viscosity (cSt) | Aggregation | % apparent free volume | |||
|---|---|---|---|---|---|---|
| 23°C | 37°C | 23°C | 37°C | 23°C | 37°C | |
| Infasurf 35mg/mL | 2.5±0.3 | 3.9±0.5 | + | - | 38±3 | n.d. |
| + Dextran | 2.7±0.1 | 1.6±0.1 | ++ | ++ | 47±3 | 55±6 |
| + PEG | 4.6±0.1 | 2.4±0.1 | +++ | +++ | 63±6 | 62±7 |
| + HA | 6.8±0.1 | 5.1±0.1 | ++ | ++ | 46±5 | 30±5 |
| Survanta 25mg/mL | 92.7±5.4 | 32.5±4 | - | - | <1 | <1 |
| + Dextran | 18.2±0.5 | 12.3±0.1 | +++ | ++ | 29±12 | n.d. |
| + PEG | 6.2±0.1 | 3.9±0.1 | +++ | +++ | 49±11 | 52±6 |
| + HA | 87.8±0.4 | 32.7±0.3 | - | - | <1 | <1 |
Values are means ± s.d. after 3 determinations (viscosity) or averaging 5 frames (free volume) n.d. indicates not determined. More + indicates greater aggregation.