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. 2009 Apr 21;338:b991. doi: 10.1136/bmj.b991

Table 4.

 Studies showing association between timing of request for organ donation and consent rate for organ donation. Numbers are percentages of relatives consenting to organ donation when factor present or not

Study No studied Type of study Factors associated with consent % consenting P value
With factor Without factor
Siminoff et al,w1 2001, US 420 Retrospective data collection via chart reviews, and telephone interviews with healthcare practitioners or OPO staff, and face to face interviews with family for all donor eligible deaths Organ donation mentioned while brain death tests conducted 65 56* 0.04
DeJong et al,w3 1998, US 164 Structured telephone interview with immediate next of kin 4-6 months after death of relative Subject of organ donation brought up after family given enough time to understand that relative was brain stem dead 83 56 <0.001
Rodrigue et al,w4 2006, US 285 Retrospective structured telephone interview with next of kin of donor eligible deceased individuals Relatives thought timing of request appropriate 68 18* <0.001
Relatives thought they were given enough time to discuss donation 60 27* <0.001
Niles et al,w9 1996, US 127 Retrospective study with data collection questionnaire Organ donation requested before death 62
Organ donation requested after death 57 0.07*
Organ donation requested at same time as family told of patient’s death 25
Gortmaker et al,w2 1998, US 707 Data collected prospectively for medically suitable potential donors referred to three organ procurement organisations Request decoupled (not at same time as death notification) 72 53 <0.001
von Pohle et al,w7 1996, US 68 Retrospective chart review Request decoupled (not at same time as death notification) 86 25 <0.05
Garrison et al,w8 1991, US 155 Retrospective review Request decoupled (not at same time as death notification) 65 18 <0.05
Evanisko et al,w14 1998, US 1061 Staff questionnaire More respondents from hospitals with high donation rates (40.6%) than respondents from hospitals with low donation rates (30.0%) knew that appropriate time to bring up topic of organ donation was after brain death had been determined (decoupled); P=0.04
Rodrigue et al,w18 2003, US 1014 Structured telephone interview with next of kin Relatives felt pressured to donate 2 6 <0.001
Relatives had enough time to decide 86 58 <0.001

OPO=organ procurement organisation.

*Calculated from published data.