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Model of the mechanism of the Mg-chelatase (stoichiometry not regarded). The protein D units occur initially at least as dimers (eventually as multimers) and I as a monomer. In the preactivation step, which is magnesium and ATP dependent, the I proteins interact with the M1 motifs of the CHL D subunits. The CHL D subunits are dimerized or multimerized involving the M2C domains of D. In the chelation step, the H protein subunits interact with the M1LM2 region of CHL D.
