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. Author manuscript; available in PMC: 2010 Feb 15.
Published in final edited form as: Int J Cancer. 2009 Feb 15;124(4):772–777. doi: 10.1002/ijc.24052

Figure 5.

Figure 5

Effects of Δ15HER2-His protein on HER2/HER3 receptors. Western blot analysis of (A) SK-BR-3 and (B) MCF7 cell lysates after treatment with purified Δ15HER2-His protein at the designated concentrations. For analysis of phosphorylated Akt (p-Akt) in A) and phosphorylated HER3 (p-HER3) protein in B), cells were stimulated with heregulin (15 min, 20 ng/ml). C) Growth inhibition of SK-BR-3 cells by Δ15HER2-His protein treatment after 72 hours incubation analyzed by MTS assay. Shown are the mean ± standard deviation of triplicates.