Table 2.
MVB Diameter (in nm) | Number of Lumenal Vesicles/Section | Percentage of Lumenal Vesicles Attached to MVB Membrane | Diameter of Lumenal Vesicles (in nm) | |
---|---|---|---|---|
chmp1a chmp1b | 276.2 (±65.6) * | 1.0 * (±1.2) | 53% * | 35.6 (±7.3) |
n = 64 | n = 71 | |||
Control | 346.2 (±57) * | 5.6 * (±3.5) | 10.7% * | 35.0 (±7.5) |
n = 40 | n = 182 |
Only those endosomes labeled with the anti-RABF2A/RHA1 antibody were used for this analysis. Asterisks indicate that the difference between control and double mutant is significant at P < 0.01