Table 4.
Randomization | Final HDRS | Maintenance medication | Time to relapsea |
---|---|---|---|
Fast Left | 2 | zaleplon 10 mg, lithium 600 mg, carbamezepine 800 mg, lorazepam 1 mg | 2 weeks |
Fast Left | 4 | No medication | 2 weeks |
Fast Left | 7 | fluoxetine 20 mg, quetiapine 400 mg | No relapse |
Fast Left | 8 | No medication | No relapse |
Fast Left | 10 | lorazepam 1 mg bid, tranylcypromine 10 mg bid | 2 weeks |
Sham | 10 | No medication | 1 month |
Slow Right | 10 | paroxetine 10 mg | 3 months |
Slow Right | 15 | Olanzapine 10 mg qhs, valproic acid 250 mg bid | 1 month |
Slow Right | 17 | No medication | 2 months (not seen at 3 months) |
Subjects were started on medication by the treating physician and assessed at 2 weeks, 1, 2, and 3 months to determine if they met criteria for relapse.
Abbreviations: HDRS, Hamilton Depression Rating Score.