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Schematic representation of the Id1-induced cellular hyperproliferation and abundant keratin 10 production pathways in keratinocytes. CD1: cyclin D1; Cdks: cyclin-dependent kinases (cdks 4/6); Rb: retinoblastoma; Rb-P: phosphorylated Rb; E2F: a transcription factor that drives the Go/G1-to-S phase transition of cells.
