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. 1999 Mar 2;96(5):1953–1958. doi: 10.1073/pnas.96.5.1953

Figure 1.

Figure 1

Structures of FKpYEEI and SLFpYEEI. The C21 allyl group of FK506, which is required for calcineurin binding, was used to link the pYEEI peptide, effectively eliminating any immunosuppressive activity of the FKpYEEI molecule.