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Ovarian steroid treatment increases OT receptor density in the anterior pituitary. Administration of 20 μg of 17-β E2 significantly (**, P < 0.01) increased the amount of OT receptor protein in the anterior pituitary compared with untreated OVX rats. Likewise, the administration of E2 + P4 significantly (*, P < 0.05) increased the amount of OT receptor protein in the anterior pituitary compared with OVX rats. No significant difference was observed between OVE- and OVEP-treated rats.
