Table 3.
Genotype distributions and allele frequencies of IDE gene polymorphism in DAT patients with and without affective disturbance after stratification according to ApoE ε4 allele.
| IDE | IDE without ApoE ε4 | |||||
|---|---|---|---|---|---|---|
| DAT with affective disturbance | DAT without affective disturbance | DAT with affective disturbance | DAT without affective disturbance | |||
| Gene polymorphism | ||||||
| T/T (%) | 33 (48.5) | 102 (73.4) | 15 (41.7) | 53 (79.1) | ||
| T/C (%) | 30 (44.1) | 33 (23.7) | 17 (47.2) | 11 (16.4) | ||
| C/C (%) | 5 (7.4) | 4 (2.9) | 4 (11.1) | 3 (4.5) | ||
| χ 2 value | 12.66 | 14.66 | ||||
| P-value | .0018* | .0007** | ||||
|
| ||||||
| Allele frequency | ||||||
| T allele, % | 70.6 | 85.3 | 65.3 | 87.3 | ||
| C allele, % | 29.4 | 14.7 | 34.7 | 12.7 | ||
| χ 2 value | 12.48 | 14.01 | ||||
| P-value | .0004+ | .0002++ | ||||
*P = .0126; **P = .0049, +P = .0028; ++P = .0014 after Bonferroni correction.