Skip to main content
. 1999 Mar 2;96(5):1965–1970. doi: 10.1073/pnas.96.5.1965

Figure 3.

Figure 3

Schematic view of the crayfish CP. Black areas in the CP indicate, from left to right, the short putative signal peptide with cleavage site (↓), the lysine-rich region (K-rich), the glutamine-rich region (Q-rich), and the region with sequence similarity to the vWF D-domain (vWF-D). Also indicated are putative N-glycosylation sites (♦), and the characteristic processing site that is not cleaved in the CP (RVRR). To illustrate the sequence similarity, the schematic view of an insect (Athalia rosae) VTG (36) is added below (VTG), where regions with sequence similarity are indicated as two gray areas, one short N-terminal region (27% identity to the CP sequence; see also Fig. 4A), and a long region spanning the C-terminal two thirds of the protein (20% identity to the CP sequence; see also Fig. 4 B and C). Black areas in the VTG indicate, from left to right, the putative signal peptide with cleavage site (↓), the two polyserine stretches (S) on each side of the proteolytic processing site in the VTG (RQAR, ↓), and the region with sequence similarity to the vWF D-domain (vWF-D).