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. 2009 Apr 14;7:25. doi: 10.1186/1479-5876-7-25

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Copyright © 2009 Koo et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Immunohistochemical analysis of p16^INK4astaining in endometrial adenocarcinomas. (a) Photomicrograph revealed adenocarcinoma of endometrium, endometroid type, H&E stain. (b) Photomicrograph revealed tumor with more predominant p16^INK4astaining at nuclei than that at cytoplasms. Diffusely moderately positive nucleic staining and no cytoplasmic staining were identified. (c) Photomicrograph revealed tumor with more predominant p16^INK4astaining at cytoplasms than that at nuclei. Diffusely moderately positive cytoplasmic staining and focally weakly nucleic staining were identified. (d) Photomicrograph revealed tumor with dual prdominat p16^INK4astaining at both cytoplasms and nuclei. Diffusely strongly positive cytoplasmic staining and nucleic staining were identified. All photomicrographs a, b, c, d were taken in median-powered, ×200.