Table 2.

Mechanics

	WT untreated	WT treated	Brtl untreated	Brtl treated
6-wk CSA (mm2)	1.1 ± 0.2	1.4 ± 0.3	0.75 ± 0.11‡	0.77 ± 0.11†§
6-wk cortical thickness (mm)	0.25 ± 0.03	0.41 ± 0.11*	0.18 ± 0.03‡	0.25 ± 0.06*§
6-wk bending moment of inertial (mm4)	0.23 ± 0.06	0.31 ± 0.11	0.13 ± 0.03‡	0.12 ± 0.03†§
6-wk BV/TV	0.16 ± 0.05	0.31 ± 0.05*	0.10 ± 0.03‡	0.31 ± 0.07*†
6-wk trabecular number (1/mm)	5.0 ± 1.3	9.2 ± 1.3*	3.3 ± 0.8‡	9.7 ± 2.1*†
6-wk trabecular thickness (mm)	0.031 ± 0.002	0.034 ± 0.002	0.030 ± 0.002	0.031 ± 0.002
6-wk stiffness (N/mm)	204.4 ± 40.7	258.5 ± 51.3	152.5 ± 40.5	141.3 ± 37.4†§
6-wk yield load (N)	22.0 ± 4.5	28.2 ± 7.3	15.6 ± 3.8‡	13.0 ± 2.9§
6-wk ultimate load (N)	32.1 ± 4.7	36.7 ± 7.0	20.7 ± 5.9‡	19.2 ± 3.3†§
6-wk post-yield displacement (mm)	0.22 ± 0.09	0.11 ± 0.05	0.10 ± 0.06	0.14 ± 0.07
6-wk predicted strength (MPa)	115.3 ± 14.9	103.3 ± 12.6	108.5 ± 20.4	103.9 ± 9.2
6-wk elastic modulus	3443.2 ± 431.5	3306.8 ± 652.2	4377.6 ± 807.1‡	4319.4 ± 730.1†§
12-wk CSA (mm2)	1.0 ± 0.1	1.4 ± 0.3*	0.86 ± 0.11‡	1.0 ± 0.2*§
12-wk cortical thickness (mm)	0.24 ± 0.03	0.37 ± 0.13*	0.22 ± 0.02‡	0.27 ± 0.07*§
12-wk bending moment of inertial (mm4)	0.19 ± 0.04	0.33 ± 0.01*	0.13 ± 0.04‡	0.19 ± 0.05*§
12-wk BV/TV	0.10 ± 0.04	0.25 ± 0.06*	0.07 ± 0.04‡	0.21 ± 0.06*†§
12-wk trabecular number (1/mm)	3.4 ± 1.2	7.7 ± 1.5*	2.6 ± 1.7‡	6.9 ± 1.7*†
12-wk trabecular thickness (mm)	0.030 ± 0.003	0.032 ± 0.002	0.029 ± 0.003	0.030 ± 0.003
12-wk stiffness (N/mm)	311.5 ± 60.3	377.9 ± 72.5*	255.1 ± 54.8‡	280.9 ± 76.7§
12-wk yield load (N)	23.5 ± 4.8	25.6 ± 5.0	20.1 ± 4.1‡	22.5 ± 5.8
12-wk ultimate load (N)	38.0 ± 7.3	43.1 ± 6.5*	29.3 ± 5.0‡	33.3 ± 6.4*†§
12-wk post-yield displacement (mm)	0.17 ± 0.06	0.15 ± 0.04	0.11 ± 0.06‡	0.10 ± 0.05†§
12-wk predicted strength (MPa)	152.3 ± 16.7	120.1 ± 23.1*	157.6 ± 23.7	137.6 ± 24.0*†§
12-wk elastic modulus	6300.1 ± 1061.9	5119.7 ± 1241.2*	7731.0 ± 1383.4	5796.2 ± 1219.8*†§

Values are mean ± SD.

* p < 0.05 between untreated and treated.

^† p < 0.05 between untreated WT and treated Brtl.

^‡ p < 0.05 between untreated WT and Brtl.

^§ p < 0.05 between treated WT and treated Brtl.