Table 1.
Basic characteristics of non-occupationally lead exposed subjects.
| All non lead exposed participants (N=101) | ALAD genotype | P | ||
|---|---|---|---|---|
| GG (N=84) | GC (N=17) | |||
|
Demographics and Clinical | ||||
| Sex (Male/Female) | 73/28 | 61/23 | 12/5 | 0.54 |
| Age (years) | 43.4 (11.9) | 43.2 (11.9) | 44.5 (12.2) | 0.68 |
| Smoking (Yes/No) | 55/46 | 45/39 | 10/7 | 0.81 |
| Height, cm | 166.3 (8.3) | 166.4 (8.2) | 165.5 (9.2) | 0.66 |
| Weight, kg | 65.0 (13.7) | 65.3 (14.4) | 63.8 (9.6) | 0.68 |
| Body mass index, kg/m2 | 23.4 (4.1) | 23.4 (4.2) | 23.3 (3.6) | 0.94 |
| SBP, mmHg | 130.2 (18.8) | 128.7 (17.4) | 137.7 (23.9) | 0.15 |
| DBP, mmHg | 78.8 (13.0) | 78.3 (12.6) | 81.1 (15.1) | 0.43 |
|
Complete Blood Counts | ||||
| White blood cell count, 103/μL | 61.2 (14.7) | 59.7 (13.8) | 68.4 (17.6) | 0.02 |
| Red blood cell count, 106/μL | 465.6 (41.6) | 465.1 (42.2) | 468.1 (40.0) | 0.79 |
| Hemoglobin, g/dL | 14.4 (1.6) | 14.3 (1.6) | 14.7 (1.7) | 0.37 |
| Hematocrit, % | 43.7 (4.0) | 43.6 (4.0) | 44.1 (4.3) | 0.65 |
| Platelet count, 103/μL | 24.9 (4.9) | 24.9 (4.6) | 25.0 (6.1) | 0.94 |
|
Biochemical | ||||
| AST/GOT, IU/l # | 22.2 (1.4) | 22.1 (1.4) | 22.4 (1.4) | 0.90 |
| ALT/GPT, IU/l # | 22.7 (1.8) | 22.8 (1.9) | 22.0 (1.6) | 0.81 |
| γ-GTP, IU/l | 34.0 (2.1) | 32.8 (2.0 | 40.9 (2.6) | 0.38 |
| Total cholesterol, mg/dL | 199.6 (36.3) | 196.9 (35.1) | 212.8 (40.1) | 0.10 |
| Triglyceride, mg/dL # | 105.9 (1.8) | 105.7 (1.9) | 107.1 (1.8) | 0.93 |
| HDL cholesterol, mg/dL # | 53.4 (1.3) | 52.9 (1.3) | 55.6 (1.3) | 0.45 |
| Blood urea nitrogen, mg/dL | 13.6 (3.5) | 13.6 (3.6) | 13.5 (2.8) | 0.90 |
| Serum creatinine, mg/dL | 0.81 (1.2) | 0.81 (1.2) | 0.78 (1.2) | 0.40 |
| Serum uric acid, mg/dL | 5.34 (1.3) | 5.38 (1.3) | 5.12 (1.2) | 0.45 |
| Lactate dehydrogenase, IU/l # | 181.6 (1.1) | 180.9 (1.2) | 185.2 (1.1) | 0.54 |
| Fasting blood sugar, mg/dL # | 95.6 (1.2) | 96.2 (1.2) | 92.8 (1.2) | 0.49 |
| Fasting blood sugar, mg/dL # | 4.98 (1.1) | 4.96 (1.1) | 5.09 (1.2) | 0.44 |
|
Outcome index | ||||
| Blood lead level, μg/dL | 3.38 (1.9) | 3.18 (1.8) | 4.35 (2.4) | 0.02 |
All values are mean (SD) except the value mentioned with the specific symbol; # Geometric mean (GSD)
BMI is calculated as weight (kg)/height (m2)
SBP: Systolic blood pressure, DBP: Diastolic blood pressure
AST/GOT:aspartate aminotransferase/glutamic oxaloacetic transaminase.
ALT/GPT: for alanine aminotransferase/glutamic pyruvic transaminase.
γ-GTP: gamma-glutamyl transpeptidase
HDL cholesterol: High density lipoprotein cholesterol
*Significant P value <0.05 in Student's t-test or χ2 test.