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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Genomics. 2008 Nov 11;93(3):205–212. doi: 10.1016/j.ygeno.2008.09.016

Figure 4. Divergence from the L1 endonuclease cleavage site.

Figure 4

The results indicate a large percentage of loci with a greater number of differences from the classical L1 endonuclease cleavage site seen in Target-primed Reverse Transcription. Atypical motifs of TPRT endonuclease cleavage sites exist, but a careful examination as compared to the cleavage sites found in NCAI, showed that no insertions at atypical TPRT cleavage sites, providing supplementary evidence of endonuclease-independent insertion.