Bar graphs showing means weights of the bulbospongiousus muscles (BSM) in grams, ± standard error of the mean, for animal subjects used for dopamine transporter (DAT) binding assays (A) and norepinephrine transporter (NET) binding assays (B). Data from animals that were sham-operated (CRTL), gonadectomized (GDX) and gonadectomized and supplemented with testosterone propionate (GDX-TP) or estradiol (GDX-E) for 4 or 28 days are shown separately. As expected, there were significant effects of hormone treatment on the weights of these androgen-sensitive muscles for both time points, and BSM weights in both the 4- and 28-day GDX and GDX-E groups were significantly less (*) than those in the corresponding CTRL and GDX-TP cohorts.