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One hIAPP aggregation pathway that is consistent with our data. Labeled residues in register at each assembly stage are denoted with colored circles (purple, Val-17; red, Ala-25; cyan, Leu-27; blue, Ala-13; yellow, Ala-8; green, Val-32). Thick black arrows indicate the β-strand, whereas the portion of the peptide in random coil or ordered loop is shown in gray.
