Skip to main content
. Author manuscript; available in PMC: 2010 Mar 17.
Published in final edited form as: Neuroscience. 2009 Mar 17;159(2):427–437. doi: 10.1016/j.neuroscience.2009.01.022

Fig. 1. Decreased neurotransmitters in brain of DKO mice.

Fig. 1

(A) Western blot of whole brain showing expression of IA-2 and IA-2β in WT, but not DKO mice. (B) Concentration of norepinephrine, dopamine and serotonin in the brain of WT and DKO mice at 12 and 30 weeks of age as determined by HPLC. Each group represents 6 mice. Data are expressed as mean ± SEM. *P < 0.05, **P<0.01, ***P<0.001. WT mice (open bars); DKO mice (closed bars).