Effect of parthenolide on cell-cycle distribution in MV4-11 cells. MV4-11
cells were placed in serum-free medium to synchronize the cell cycle for 24 h.
Cells were then treated with parthenolide (0, 3, and 10 μM) for 24 h.
Cell-cycle distribution was determined by flow cytometry. A, representative
sets of histogram for MV4-11 cells (A) and 3 μM (B) and 10 μM (C)
parthenolide-treated cells. Percentages of cells in SubG1,
G0/G1, S, and G2/M phase are shown as insets
for each experiment.