Figure 4.
Endothelium-independent relaxation of aorta segments from apoE-/- mice treated with C60 fullerenes by i.p. injection. The response is expressed as the percent relaxation of the precontraction tension produced by PGF2α. Each point on the curve represents the cumulative response at each concentration of sodium nitroprusside (SNP). The data are expressed as the mean and SEM. # denotes a significant effect on EC50 compared to the control group (P < 0.05, ANOVA with unequal variance between groups).