Table 6.
Median Fasting Lipid and Metabolic Parameters at Baseline and Week 48
|
ABC/3TC/ZDV N = 138 |
ATV+3TC/ZDV N = 140 |
|||||
| Median (range) | Number Tested (Baseline, Week 48) |
Baseline | Week 48 | Number Tested (Baseline, Week 48) |
Baseline | Week 48 |
| TC (mg/dL) | 131, 93 | 162 (95–255) |
176 (102–305) |
137, 93 | 160 (71–276) |
171 (68–288) |
| LDL (mg/dL) | 127, 89 | 98 (6–165) |
99 (20–198) |
133, 92 | 97 (31–200) |
101.5 (10–200) |
| HDL (mg/dL) | 131, 93 | 36.5 (6–74) |
44 (21–75) |
135, 93 | 33 (7–77) |
44 (18–90) |
| TG (mg/dL) | 131, 93 | 113 (38–621) |
126 (42–1231) |
137, 93 | 117 (41–559) | 110 (44–407) |
| Glucose (mg/dL) | 119, 91 | 95 (60–199) |
98 (5–268) |
126, 93 | 89.5 (58–131) |
95 (72–166) |
| Insulin (μIU/mL) | 117, 79 | 10 (2–128) |
13 (2–56) |
119, 83 | 10 (2–61) |
12 (4–132) |
| HOMA-IR+ | 110, 83 | 2.2 (0.4–37.5) |
2.9 (0.4–17.3) |
112, 87 | 2.4 (0.4–19.5) |
3 (0.9–51.6) |
| QUICKI++ | 110, 83 | 0.59 (0.34–1.05) |
0.54 (0.38–1.00) |
112, 87 | 0.58 (0.37–1.00) |
0.54 (0.32–0.77) |
+HOMA-IR = [Fasting Insulin (μIU/mL) × Fasting Glucose (mg/dL))/(22.5 × 18)];
++QUICKI = 1/[log Fasting Insulin (μIU/mL)] + [log Fasting Glucose (mg/dL)]